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Updated: 2017 Aug. 1

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Warning – Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite   Conservation Score
Human Protein: AXIN1 All Species: 29.7
Human Site: S228 Identified Species: 59.39
UniProt: O15169 Number Species: 11
    Phosphosite Substitution
    Charge Score: 0.09
Phosphosite
Sequences
Species Species
Scientific Name
UniProt ID NCBI Ref Seq ID AA# Mr(Da) P-Site -7 -6 -5 -4 -3 -2 -1 0 1 2 3 4 5 6 7
Human Homo sapiens O15169 NP_003493.1 862 95635 S228 C S D Q S S G S G T G K G I S
Chimpanzee Pan troglodytes XP_001152990 821 90810 S228 C S D Q S S G S G T G K G I S
Rhesus Macaque Macaca mulatta
Dog Lupus familis XP_852321 867 95820 S228 C S D Q S S G S G T G K G I P
Cat Felis silvestris
Mouse Mus musculus O35625 863 96295 S228 C S D Q S S G S G T G K G M S
Rat Rattus norvegicus O70239 827 92266 S228 C S D Q S S G S G T G K G M S
Wallaby Macropus eugenll
Platypus Ornith. anatinus XP_001508740 844 93228 S220 M S N N G L G S L K V V C G Y
Chicken Gallus gallus O42400 841 94913 S228 Y S D P S S G S G T G K G L P
Frog Xenopus laevis Q9YGY0 842 94441 S228 Y S D Q S S G S G T G K G P S
Zebra Danio Brachydanio rerio P57094 835 94310 S231 F S D Q S S V S G N G K V L P
Tiger Blowfish Takifugu rubipres
Fruit Fly Dros. melanogaster Q9V407 745 81700 Q219 T T A S G K Q Q L P Q L V P P
Honey Bee Apis mellifera XP_001120373 693 78297 E182 V F D A V Q L E V E R L I N E
Nematode Worm Caenorhab. elegans
Sea Urchin Strong. purpuratus XP_781992 855 95982 G227 S E G C S S N G S N G H H V Q
Poplar Tree Populus trichocarpa
Maize Zea mays
Rice Oryza sativa
Thale Cress Arabidopsis thaliana
Baker's Yeast Sacchar. cerevisiae
Red Bread Mold Neurospora crassa
Conservation
Percent
Protein Identity: 100 94.6 N.A. 86.6 N.A. 87 84.2 N.A. 43.2 73 67.5 64 N.A. 21.8 27.2 N.A. 33
Protein Similarity: 100 95.1 N.A. 91.2 N.A. 91.1 88.1 N.A. 59.4 82.9 79.4 74.8 N.A. 38 42.4 N.A. 50.3
P-Site Identity: 100 100 N.A. 93.3 N.A. 93.3 93.3 N.A. 20 73.3 86.6 60 N.A. 0 6.6 N.A. 20
P-Site Similarity: 100 100 N.A. 93.3 N.A. 100 100 N.A. 26.6 80 86.6 66.6 N.A. 6.6 6.6 N.A. 26.6
Percent
Protein Identity: N.A. N.A. N.A. N.A. N.A. N.A.
Protein Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Identity: N.A. N.A. N.A. N.A. N.A. N.A.
P-Site Similarity: N.A. N.A. N.A. N.A. N.A. N.A.
Phosphosite
Consensus
Position -7 -6 -5 -4 -3 -4 -5 0 +1 +2 +3 +4 +5 +6 +7
% Ala: 0 0 9 9 0 0 0 0 0 0 0 0 0 0 0 % A
% Cys: 42 0 0 9 0 0 0 0 0 0 0 0 9 0 0 % C
% Asp: 0 0 75 0 0 0 0 0 0 0 0 0 0 0 0 % D
% Glu: 0 9 0 0 0 0 0 9 0 9 0 0 0 0 9 % E
% Phe: 9 9 0 0 0 0 0 0 0 0 0 0 0 0 0 % F
% Gly: 0 0 9 0 17 0 67 9 67 0 75 0 59 9 0 % G
% His: 0 0 0 0 0 0 0 0 0 0 0 9 9 0 0 % H
% Ile: 0 0 0 0 0 0 0 0 0 0 0 0 9 25 0 % I
% Lys: 0 0 0 0 0 9 0 0 0 9 0 67 0 0 0 % K
% Leu: 0 0 0 0 0 9 9 0 17 0 0 17 0 17 0 % L
% Met: 9 0 0 0 0 0 0 0 0 0 0 0 0 17 0 % M
% Asn: 0 0 9 9 0 0 9 0 0 17 0 0 0 9 0 % N
% Pro: 0 0 0 9 0 0 0 0 0 9 0 0 0 17 34 % P
% Gln: 0 0 0 59 0 9 9 9 0 0 9 0 0 0 9 % Q
% Arg: 0 0 0 0 0 0 0 0 0 0 9 0 0 0 0 % R
% Ser: 9 75 0 9 75 75 0 75 9 0 0 0 0 0 42 % S
% Thr: 9 9 0 0 0 0 0 0 0 59 0 0 0 0 0 % T
% Val: 9 0 0 0 9 0 9 0 9 0 9 9 17 9 0 % V
% Trp: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % W
% Tyr: 17 0 0 0 0 0 0 0 0 0 0 0 0 0 9 % Y
% Spaces: 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 % _